Jeremiah Scharf, MD, PhD
Dr. Scharf is a behavioral neurologist and neuropsychiatric geneticist who works at the interface between neurology and psychiatry, employing statistical and molecular genetics techniques as well as clinical research tools to investigate the etiology and pathogenesis of Tourette Syndrome (TS) and related neurodevelopmental disorders as model neuropsychiatric illnesses.
Clinically, Dr. Scharf directs the Neurology Tic Disorders Unit within the Division of Movement Disorders at Massachusetts General Hospital (MGH) and the Division of Cognitive and Behavioral Neurology at Brigham and Women’s Hospital, Boston, Mass. He is also co-director of the MGH-TAA National TS Center of Excellence.
Dr. Scharf’s research lab, located within the Psychiatric and Neurodevelopmental Genetics Unit (PNGU) at Massachusetts General Hospital and the MGH Center for Genomic Medicine, is focused on identifying genetic and non-genetic risk factors that predispose individuals to TS and its co-occurring conditions, including OCD, ADHD, body-focused repetitive behaviors and autism spectrum disorders. Using a range of experimental approaches, Dr. Scharf aims to understand how genetic variation contributes to the unique and overlapping clinical features of these disorders which in turn may provide novel insight into the underlying biology of these conditions and ultimately lead to improved prognosis and treatment.
Dr. Scharf is co-chair of the Tourette Association of America International Consortium for Genetics with Dr. Carol Mathews, a member of the Steering Committees for the International OCD Foundation Genetics Consortium and the Body-Focused Repetitive Behaviors (BFRB) Precision Medicine Initiative, and is the Data Access Representative for the TS and OCD Workgroup of the Psychiatric Genomics Consortium. He also serves on the Scientific Advisory Boards of the TAA and the TLC Foundation for BFRBs.